|
KMID : 1143020220270020119
|
|
Archives of Hand and Microsurgery
2022 Volume.27 No. 2 p.119 ~ p.124
|
|
|
The role of skin antisepsis in upper extremity surgery to reduce surgical site infection: a comparison between single and triple regimens
|
|
Hwang Ji-Sup
Lee Dong-Min
Lee Yo-Han
|
|
|
Abstract
|
|
|
Purpose : No consensus exits regarding preoperative skin antisepsis for upper extremity surgery. We aimed to determine whether the use of povidone-iodine only (single regimen) instead of povidone-iodine and alcohol-chlorhexidine (triple regimen) resulted in an increased rate of surgical site infection (SSI), and to detect any associated factors that increased the infection risk.
Methods : A cross-sectional, retrospective review of medical records was conducted for patients who underwent upper extremity surgery from March 2020 to February 2021. Either the single or triple regimen was used for preoperative skin antisepsis. The rate of SSI was compared based on a marked elevation of C-reactive protein (CRP) at 2 weeks after surgery, superficial SSI, and deep SSI. Logistic regression analysis was performed to identify factors associated with SSI among the evaluated parameters.
Results : Among 175 patients (male, 81 and female, 94), the single regimen was used in 78 patients (44.6%) and the triple regimen in 97 patients (55.4%). The single regimen (odds ratio [OR], 2.425; 95% confidence interval [CI], 1.040-5.655) and a surgical procedure using a metal implant (OR, 3.602; 95% CI, 1.184-10.953) were significantly associated with a marked CRP elevation at 2 weeks. However, there was no difference in SSI rates between the single and triple regimens. Diabetes mellitus (OR, 6.636; 95% CI, 1.259-34.969) was the only factor significantly associated with superficial SSI through logistic regression analysis.
Conclusion : Our study suggests that the single regimen resulted in a longer CRP elevation than the triple regimen, but was similarly effective in preventing SSI for upper extremity surgery.
|
|
|
KEYWORD
|
|
|
Skin antisepsis, Povidone-iodine, Surgical wound infection
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|